From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic proteins (BMPs) are summarized in this topical volume. Distinguished scientists present reviews on a range of scientific topics, including biochemistry, biology, molecular biology and preclinical animal studies on spinal fusion, cartilage repair, craniofacial and dental reconstruction using BMPs, as well as approved clinical applications in human bone non-unions.
This book provides a resource not only for experts in the field, but also for...
From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic prot...
S. Vukicevic Slobadan Vukicevic Slobodan Vukicevic
There is a great interest for biological regeneration of tissues in particular by using growth factors. BMPs are at this time the only growth and differentiation factors discovered with a high potential in inducing regeneration of tissues like bone, cartilage, kidney, brain etc. Other indications for BMPs in clinical medicine have been further explored in laboratories worldwide, including new discoveries in the field of nephrology and oncology (e.g. in renal osteodystrophy, prostate cancer in animals and metastatic breast cancer). In the field of structur/function analysis of BMPs new...
There is a great interest for biological regeneration of tissues in particular by using growth factors. BMPs are at this time the only growth and diff...
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and progenitor cell types are required principles to engineer a functional tissue locally, the inductive signal is a prerequisite to trigger the growth and differentiation of responding cells in space and time. Bone morphogenetic proteins (BMPs), also called growth and differentiation factors (GDFs), originally identified from bone have been successfully used to regenerate the bone in humans. Most recent preclinical data suggests that BMPs have a...
Tissue engineering is gaining interest as it is applied for regeneration of organs to attain their lost function. Although resorbable scaffolds and...
From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic proteins (BMPs) are summarized in this topical volume. Distinguished scientists present reviews on a range of scientific topics, including biochemistry, biology, molecular biology and preclinical animal studies on spinal fusion, cartilage repair, craniofacial and dental reconstruction using BMPs, as well as approved clinical applications in human bone non-unions.
This book provides a resource not only for experts in the field, but also for...
From the basic science to potential and approved clinical applications the most recent data in the rapidly growing field of bone morphogenetic prot...
Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific discoveries and clinical reports on their use from institutions all over the world. The potent effica- cy of BMPs in almost all crucial developmental events as well as during regenera- tion of various organs such as bone, kidney, brain, liver, heart etc., has positioned BMPs at the center of scientific interest. Many of these aspects are covered in this new PIR volume. Their role in development, biology, signal transduction, kidney...
Since the discovery of the bone morphogenetic proteins (BMPs) more than 15 years ago, there has been an unpredicted explosion of both basic scientific...
