This book provides an overview of recent advances in radiation oncology, many of which have originated from physics and engineering sciences. After an introductory section on basic aspects of 3D medical imaging, the role of 3D imaging in the context of radiotherapy is explored in a series of chapters on the various modern imaging techniques. A further major section addresses 3D treatment planning for conformal radiotherapy, with consideration of both external radiotherapy and brachytherapy. Subsequently the modern techniques of 3D conformal radiotherapy are described, including...
This book provides an overview of recent advances in radiation oncology, many of which have originated from physics and engineering sciences. After...
The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50% are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well...
The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000,...
Although decades of laboratory and clinical research have led to incremental improvement in treatment outcome, lung cancer remains one of the most deadly diseases. This volume is unique in being devoted solely to the radiation oncology of lung cancer, and will be of great value to all who are involved in the diagnosis and treatment of the disease. Both non-small cell and small cell lung cancer are considered in detail. Current state-of-the-art treatment strategies and novel approaches that promise further improvements in outcome are explained and evaluated, with the aid of high-quality...
Although decades of laboratory and clinical research have led to incremental improvement in treatment outcome, lung cancer remains one of the most ...
Over recent decades, combined modality treatment has drastically improved the cure rates for various malignant tumors. Further progress is expected through the design of sound combinations involving recently developed drugs. The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on different forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies. The second part of the book...
Over recent decades, combined modality treatment has drastically improved the cure rates for various malignant tumors. Further progress is expected...
Statistically speaking, head and neck cancer per se (excluding melano ma and basal cell carcinoma) does not outwardly seem to pose a serious threat - 27,500/870,000 total cancer cases estimated for 1984 (or 3.2% of all cancers) and 9,350/450,000 total cancer deaths in 1984 (or 2.1 %) for the United States. Yet in clinical practice, by the time that diagnosis is made, more than 60% of oral cancers have already spread to the nearby lymph node system. And while the overall five-year survival rate for localized oral cancer is 67%, this rate decreases drastically to only 25% when the original...
Statistically speaking, head and neck cancer per se (excluding melano ma and basal cell carcinoma) does not outwardly seem to pose a serious threat - ...
In the last decade brachytherapy experienced a dramatic up- swing. The introduction of new radioisotopes with favorable nuclear physical properties, computer-assisted dosimetry, and the advent of modified afterloading techniques set off this revolutionary development. The main topics discussed in this book are brain tumors and tumors of the head and neck, choroidal melanoma, breast cancer, carcinoma of the anal ca- nal, carcinoma of the prostate, and gynecological malignan- cies.
In the last decade brachytherapy experienced a dramatic up- swing. The introduction of new radioisotopes with favorable nuclear physical properties, c...
The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a...
The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of can...
The diagnosis of cancer in a child is a devastating finding not only to the parents but often to the child. Even though the situation is relatively easy to accept among adults, it is difficult to accept among children because of their general helpless state. The advances that have been made in the management of a child with cancer in the last 20 years have been dramatic in character. These have occurred not only by virtue ofthe contributions from early diagnosis and more precise staging but also from the contribu tions made by surgery, radiation therapy, and the more widespread utilization of...
The diagnosis of cancer in a child is a devastating finding not only to the parents but often to the child. Even though the situation is relatively ea...
In the last two decades, there has been a major increase in the actual numbers of women diagnosed with breast cancer (from 65000 new cases 20 years ago in the United States to 183000 in 1993). Concomitant with this has been a shift toward making the diagnosis earlier and toward diagnosing an earlier stage ofthe disease (more than 70% of diagnoses were of advanced-stage disease two decades ago, whereas more than 70% of diagnoses are now earlier-stage disease in 1992). These changes are clearly related to the woman's greater sensitivity to abnormalities in the breast and her seeking medical...
In the last two decades, there has been a major increase in the actual numbers of women diagnosed with breast cancer (from 65000 new cases 20 years ag...
The use of hyperthermia in radiation oncology is well established. Many publications cover the whole field of possibilities and problems of this therapeutic modality. The new development of interstitial and intracavitary hyperthermia, however, is not well known: there are only a few relevant publications in different journals. Therefore, it was appropriate that SAUER and SEEGENSCHMIEDT organized an international meeting on this topic, where experiences with this new and promising technique were compiled and discussed by experts. The papers of this symposium together with additional review...
The use of hyperthermia in radiation oncology is well established. Many publications cover the whole field of possibilities and problems of this thera...