This volume details the theories, mechanisms, technologies and trends for solving qualitative and quantitative problems in diverse areas of analytical research - emphasizing physicochemical principles. It focuses on deriving simpler and more extensive chemiluminescence (CL) detectors reflecting miniaturization trends, including narrow-bone and capillary liquid chromatography versus high-performance liquid chromatography and miniaturized high-performance thin-layer chromatography. It also covers the sensitivity, selectivity, wide detection range and versatility of CL-based methodologies.