This timely and compact monograph addresses how to determine drug permeability across the blood-brain barrier more effectively. Focusing on the physiological mechanisms that influence the passage of agents into the brain, the book covers the latest research on the blood-brain barrier, the current problems of and solutions to drug delivery to the central nervous system (CNS), existing strategies, and prospects for future research.
Avoid excessive in vivo experimentation and utilize timesaving in vitro techniques.
A concise reference with reviews from nearly 40 international specialists...