Die von FLECKENSTEIN unter dem Begriff "Kalziumantagoni sten" zusammengefaBte Gruppe von Pharmaka gewinnt zuneh mende klinische Bedeutung. Die antianginose Wirkung und die antihypertensive Wirkung beispielsweise sind zwar schon seit vielen Jahren bekannt, ihre klinische Bedeutung wird aber in den 80er Jahren mehr und mehr geschatzt. In der praktischen Anwendung stand zunachst die instabile bzw. spastische Angina pectoris im Vordergrund. Heute werden Kal ziumantagonisten auch bei der stabilen Form eingesetzt. Die Rolle von Kalziumantagonisten bei der Behandlung des frischen Myokardinfarktes...

Sinee the introduetion of Gallopamil in 1983 this drug has been applied in similar indications as Verapamil. Predominantly pat ients with stable or unstable angina peetoris, with hypertension, and hypertrophie eardiomyopathy have been treated. As far as ean be judged from preliminary clinieal experienee Gallopamil aehieves similar results as Verapamil with mueh lower doses. Instead of 3 times 160 mg Verapamil 2 to 3 times 50 mg Gallopamil ean be applied. Although the speetrum of side effects ofboth drugs is similar it is evident that oeeasionally patients ean tolerate one better than the...

Das Anliegen dieses Buches ist, die Bedeutung der rontgenologischen Herzvolumenbestimmung in der Klinik darzulegen. Man sollte sich he ute nicht mehr mit dem Ergebnis einer Rontgenuntersuchung be gniigen, das z. B. Iautet: "Das Herz erscheint Ieicht vergroBert. " Uberall in der Wissenschaft und Praxis streben wir nach MaB und Zahl, warum nicht auch bei der HerzgroBenbestirnmung? Schon zu Beginn der klinischen Rontgenologie urn die J ahrhundert wende bestimmte Moritz die HerzgroBe mitteis Orthodiagraphie, einer flir die Praxis zu umstandlichen Methode; 1916/17 errnittelte Rohrer die HerzgroBe...

The aim of this book is to give an up to date account of recent developments in the field of cardiomyopathy. Many authors, all experienced workers in their fields, - most from Germany - have contributed to this volume. It would appear that the diagnosis of cardiomyopathy is now made more often than it was 10 years ago. The reason for this is probably not that the incidence of the disease has increased, but that it is better recognized. Where conventional clinical investigation may have failed to define the underlying disease process in a given patient, improved or more widely used diagnostic...

First described in 1907 by Schicke but recognized as a clinical entity only as recently as 1958, when Teare published the pathologic findings in patients with hypertrophic cardiomyopathy (HeM), an explosion of knowledge about this fascinating disease has occurred, which has caused a profound evolution of our understanding of its broad pathophysiologic and clinical spectrum. Progress has been particularly rapid in the past few years when M-mode echocardiography, and more recently 2-dimen sional echocardiography have been applied to the study ofHCM. In addition to new insights as to what the...

This volume contains the proceedings of the Fourth International Symposium on Coronary Heart Disease, held in Frankfurt/Federal Republic of Germany. In 1970, when the fIrst symposium was held, the whole range of diagnostic and therapeutic measures was covered, but since then interest in coronary heart disease has increased so considerably that the fourth symposium was restricted to only two therapeutic aspects, angioplasty and intracoronary thrombolysis. It can be noted with pleasure that European cardiologists, namely Andreas Griintzig and Peter Rentrop, have made essential contributions to...

Although nitroglycerin is one of the oldest drugs in cardiology the problem of tolerance is a scientific challenge of today. The proceedings of this symposium highlight the most re- cent questions related to this topic. Apparently, partial tolerance, or rather partial decrease in sensitivity, can arise during nitrate therapy. Probably this is the consequence of a partial readjustment of the vascular system. This readjustment refers particularly to the arterial system, i.e., to the hypoten- sive effect of nitrates in the standing position. A similar effect on the venous side is not present. On...

This book aims to provide an easily read general account of clinical cardiology. It is primarily designed to meet the needs of medical students, but should be helpful to advanced students in nursing and paramedical fields, as well as providing a review text for medical interns and residents. The book may help to practice modern medicine in a humane way. This means utilizing all possibilities available, but, at the same time, recognizing their limitations. Since progress in the field of cardiology advances rapidly the physician can only keep up with it by understanding diagnostic and...