Stroke is one of the most common causes of death and subcortical stroke accounts for 20-30% of all cerebrovascular infarcts. Our understanding of stroke processes in general, and subcortical stroke in particular, has advanced considerably in recent years. Research findings from the fields of neurochemistry, imaging and genetics have provided insight and input to our understanding of this condition, and this new edition provides an opportunity to describe these advances, and to relate the findings to the clinical expression, neural mechanism, prognosis and treatment of subcortical stroke. In...

Stroke is a major health concern worldwide, and the epidemiological data is staggering. One in six people will have a stroke during the course of their life; it is the second most common cause of death; and stroke also ranks second among causes contributing to the global burden of disability. However, the burden of stroke can be alleviated: it is potentially preventable, treatable, and possible to manage long term. Despite continuing advances in our knowledge about this disease, there is currently still a large evidence-to- clinical practice gap in all regions. The Oxford Textbook of Stroke...