Since the introduction of laser technology into medicine, quite a number of clinical applications in orthopaedics have been developed. This text is the first to provide comprehensive guidelines and how-to-do instructions for the application of lasers in orthopaedics. These cover patient selection and decision-making as well as the benefits and risks of the clinical application of lasers in arthroscopic surgery, spine surgery and open surgery. An overview is given on the basics of laser technology and the various laser types are evaluated in terms of optimal use.