The Atlantic slave trade brought to Cuba the African slaves who created the dramatic transformation of the island from a relative backwater of Spain's colonial empire in the mid-eighteenth century to the world's richest plantation colony one hundred years later. Britain played a vital role in this transformation. British slave traders were the chief suppliers of Cuba's slaves in the eighteenth century; in the nineteenth century Britain became the greatest threat to Cuba's prosperity when she attempted to make Spain follow her example and abolish the slave trade. Dr Murray's study, based on a...

In 1791 when the Constitutional Act created a legislative assembly for Upper Canada, the colonists and their British rulers decreed that the operating criminal justice system in the area be adopted from England, to avoid any undue influence from the nearby United States. In this new study of early Canadian law, David Murray has delved into the court records of the Niagara District, one of the richest sets of criminal court records surviving from Upper Canada, to analyze the criminal justice system in the district during the first half of the nineteenth century.

Murray explores how...

Over the last several decades, the introduction of new chemotherapeutic drugs and drug combinations has resulted in increased long term remission rates in several important tumor types. These include childhood leukemia, adult leukemias and lymphomas, as well as testicular and trophoblastic tumors. The addition of high-dose chemotherapy with growth factor and hemopoietic stem cell support has increased clinical remission rates even further. For the majority of patients with some of the more common malignancies, however, palliation (rather than cure) is still the most realistic goal of...