The objective of drug discovery phase is to synthesize lead compounds, new analogs with improved potency, reduced off target activities, and physiochemical/metabolic properties suggestive of reasonable in vivo pharmacokinetics. This optimization is accomplished through empirical modification of the hit structure and/or by employing structure-based design if structural information about the target is available. The goal of present work is to design drug with minimum side effect and maximum potency. 2D QSAR is planned using Multiple Linear Regression Analysis, for achieving the goal, which can...

Globalization offers each and every member of society clear economic opportunities and benefits but it comes with substantial social costs that often appear to affect young people more as they are in their tenuous transitional status within an uncertain and rapidly evolving global context. Hence this book explores the Indian Youth experiences with globalization and its co-relationship with the law of the land. The book gives an insight to the ambiguities and contradictions that characterizes globalization, providing an assessment of its different implications on Indian Youth, its contribution...