This volume constitutes the refereed proceedings of the International Workshop on Semantics Applications, and Implementation of Program Generation, SAIG 2000, held in Montreal, Canada in September 2000. The seven revised full papers and four position papers presented together with four invited abstracts were carefully reviewed and selected from 20 submissions. Among the topics addressed are multi-stage programming languages, compilation of domain-specific languages and module systems, program transformation, low-level program generation, formal specification, termination analysis, and...