This volume of the Methods in Molecular Biology series is entirely devoted to the study of steroid receptor biology. Steroid hormone receptors represent a powerful system for the study of both the most fundamental molecular mec- nisms of gene regulation and control and the gross physiological responses of organisms to steroid hormones. Research in this field has brought forth advances in the treatment of cancer, endocrine disorders, and reproductive biology, and allowed elucidation of the fundamental biological mechanisms of gene expr- sion. In Steroid Receptor Methods: Protocols and Assays,...

Modeling complex systems is a difficult challenge and all too often one in which modelers are left to their own devices. Using a multidisciplinary approach, The Art of Software Modeling covers theory, practice, and presentation in detail. It focuses on the importance of model creation and demonstrates how to create meaningful models.
Presenting three self-contained sections, the text examines the background of modeling and frameworks for organizing information. It identifies techniques for researching and capturing client and system information and addresses the challenges of presenting...

In the modern Greek city of Thessaloniki, the ruins of a vast Jewish cemetery lie buried under the city s university. Nearby is the site of the childhood home of one of the founders of the modern Turkish state. These are tantalizing reminders of what was once the bustling cosmopolitan city of Salonica, home not just to Greeks but to thousands of Sephardic Jews, Turks, Bulgarians, and Armenians living and working peacefully alongside one another. Thessaloniki is just one example among many of what used to be. Over the past two centuries, ethnic cleansing has remade the map of Central and...