The options in antenatal and neonatal care are legion. Preferences still tend to be subjective. In spite of much publicity that has raised public expectation, an up-to-date thorough evaluation of antenatal and neonatal screening was lacking. TLhis book sets out screening approaches in a quantitative manner and will enable choices to be based on objective evidence of efficacy and, where appropriate, safety. Technical advances have sometimes been introduced uncritically and without adequate assessment. It has been assumed, perhaps naively, that the early detection of abnormality will invariable...