This thirty-ninth volume of IARC Monographs comprises considerations of a number of industrial chemicals used in the production of plastics and elastomers; some of the compounds are also used in paints and adhesives. Two compounds - dichloroacetylene and 4-vinylcyclohexene - can occur as by-products in the production or use of some of these chemicals. New data were available on some of the chemicals evaluated previously: methyl acrylate, ethylacrylate, caprolactam, 4 4'-methylene-dianiline, toluene diisocyanate, vinyl acetate, vinyl bromide, and vinylidene chloride, and these have been...

Evaluates the carcinogenic risk to humans posed by man-made mineral fibres and radon.

Evaluates the carcinogenic risk to humans posed by the consumption of chlorinated drinking-water by two chemicals used in the chlorination of drinking-water by a number of halogenated by-products formed when chlorine interacts with organic matter in water and by a selection of other halogenated compounds found in drinking-water. Chlorination was selected for evaluation because of its widespread use and because potentially carcinogenic by-products have been measured in chlorinated water. The book also includes a separate monograph on cobalt and cobalt compounds.

The volume opens...

Evaluates carcinogenic risks associated with human exposure to solar radiation and to ultraviolet radiation from medical and cosmetic devices general illumination and industrial sources. The main objective of the evaluation was to determine whether enough evidence is available to decide which segments of the radiation spectrum are responsible for its adverse effects. To this end, particular attention is given to data that shed light on the distinctive carcinogenic activity of ultraviolet A B and C radiation.

In evaluating carcinogenic potential the report also considers the...

Evaluates the carcinogenic risk to humans posed by exposure to three hepatotropic viruses: hepatitis B virus, hepatitis C viruses, and the hepatitis D virus, which exists as a satellite agent of hepatitis B virus.

Among the several viruses that can cause hepatitis, these three were selected for evaluation because of their potential to induce chronic liver infection. The most extensive monograph evaluates the large body of data suggesting a link between infection with hepatitis B virus and hepatocellular carcinoma in humans. The evaluation takes on particular importance in view of...

Evaluates the carcinogenic risk to humans posed by occupational exposures to wood dust and formaldehyde. A number of occupational situations that involve exposure to wood dust also entail exposure to formaldehyde, as in plywood and particle board manufacture, during furniture and cabinet-making, and during parquet floor sanding and varnishing.
The carcinogenic risks of wood dust are evaluated in the first monograph. The highest occupational exposures were noted to occur in wood furniture and cabinet manufacture, especially during machine sanding and similar operations, in the finishing...

Evaluates the carcinogenic risks to humans posed by exposures in the dry cleaning industry by eight chlorinated solvents and related chemicals and by an additional group of seven industrial chemicals. Dry cleaning is evaluated in the first and most extens

Evaluates the carcinogenic risk to humans posed by the therapeutic use of thirteen pharmaceutical drugs, including eight benzodiazepines and related compounds used for the treatment of anxiety and as sedatives and anticonvulsants, three triphenylethylene anti-oestrogenic compounds developed for the treatment of breast cancer, and two cholesterol-lowering agents used to treat patients at high risk for cardiovascular disease. Evaluations are based on a critical assessment of all data available for these compounds, including abundant information on pharmacokinetic and pharmacodynamic effects,...

Evaluates the carcinogenic risk to humans posed by exposure to some Aromatic Amines and Related Nitro Compounds Hair Dyes, Colouring Agents & Miscellaneous Industrial Chemicals.