The 1559-1561 expedition of Don Tristan de Luna y Arellano to Florida was at the time of Spain's most ambitious attempt yet to establish a colonial presence in southeastern North America. In June of 159, eleven ships carrying some five hundred soldiers and one thousand additional colonists, including not just Spaniards but also many of Aztec and African descent, sailed north from Veracruz, Mexico, on their way to the bay known then as Ochuse, and later as Pensacola. Finally arriving in mid-August, the colonists quickly sent word of their arrival back to Mexico and unloaded their supplies...