New Horizons for Failing Heart Syndrome brings together the latest knowledge on heart failure syndrome and the status of research on heart failure in Japan, compiling the results of the Japanese Circulation Society's second research series. Contents include the molecular mechanism of heart failure, mechanics of contraction of the failing heart, energetics of the failing heart, exercise physiology, and new aspects of management of heart failure. The Japanese Circulation Society's 3-year project for research on heart failure was conducted in two series, the first from 1988 to 1991 and...

Remarkable progress has been made in understanding and treating heart failure. Among other developments, angiotensin-converting enzyme inhibitors and b-blockers have been found to have beneficial therapeutic effects, reinforcing the view that heart failure may be both a haemodynamic and a neurohumoral disorder. The Japanese Heart Failure Society was established to curb the threat of heart failure through research, education, and clinical practice. At the Society's "Annual Scientific Meeting", molecular biologists, physiologists, clinicians, surgeons, and researchers in related fields met to...