General relativity provides our best description of gravitation in modern physics currently all observations and tests of gravitational theories have agreed with it. GR is applied in fields as diverse as fundamental astronomy, astrophysics, geodesy, physics, and space sciences, where high-accuracy observations and measurements are taken or modeled. IAU Symposium 261 summarizes the present state of applied relativity. It considers the applications of general relativity in a wide range of disciplines: geodesy, navigation, solar system ephemerides, space missions, pulsar timing, high-accuracy...