The central concern of this book is with the "prediction problem" in biomedical research. In particular, the authors examine the use of animal models to predict human responses in drug and disease research. The arguments discussed are drawn from both biological and biomedical theory (with numerous examples and case studies drawn from evolutionary biology, complex systems theory, oncology, teratology, and AIDS research), and analyses of empirical evidence (concerning, for example, data on intra- and inter-species differences revealed by recent results from genome analyses of various species,...
The central concern of this book is with the "prediction problem" in biomedical research. In particular, the authors examine the use of animal models ...
Arguing that there is a great divide between species that makes extrapolation of biochemical research from one group to another utterly invalid, this book provides the argument's scientific underpinning in accessible language, examining paediatrics, brain diseases, new surgical techniques and more.
Arguing that there is a great divide between species that makes extrapolation of biochemical research from one group to another utterly invalid, this ...