Inflammation in itself is not to be considered as a disease . . . and in disease, where it can alter the diseased mode of action, it likewise leads to a cure; but where it cannot accomplish that solitary purpose . . . it does mischief - John Hunter, A Treatise on the Blood, ITfIlammation, and Gunshot Woundr (London, 1794)1 As we reached the millennium, we recognized the gap between our scientific knowledge of biologic processes and our more limited clinical capabilities in the care of patients. Our science is strong. Molecular biology is powerful, but our therapy to help patients is weaker...
Inflammation in itself is not to be considered as a disease . . . and in disease, where it can alter the diseased mode of action, it likewise leads to...
This text brings together international experts to explore the pathophysiology, prevention, and treatment of Systemic Inflammatory Response Syndrome, Multiple Organ Dysfunction Syndrome and Multiple Organ Failure with an emphasis on injury, ischemia, and inflammation. Emphasizing material of clinical relevance to patient care, 75 chapters address development of SIRS, MODS and MOF including risk history; mechanisms of SIRS and organ failure; mediators and effectors including cytokines, biologic control of inflammation, histamine, nitric oxide; prevention and general therapy including intensive...
This text brings together international experts to explore the pathophysiology, prevention, and treatment of Systemic Inflammatory Response Syndrome, ...