Originally published in 1960, this volume contains the lectures delivered at a Cambridge Postgraduate Medical Course for consultants, senior registrars and medical research workers having haematology as one of their main laboratory or clinical interests. The course was held in December, 1959. The lectures are informative reviews of important topics in haematology, given by workers who themselves contributed to the advance of knowledge in their respective fields.

Hairy-cell leukaemia (HCL) is an established clinicopathological entity typified by a chronic picture of substantial splenomegaly, less frequent hepatomegaly, and only inconspicuous lymphadenopathy. Central to the diagnosis is the pathognomonic hairy cell (HC), a dis- tinctive mononuclear cell that circulates in varying numbers and infiltrates a variety of organs, including the bone marrow and spleen. Peripheral pancytopenia is often present, and circulating HCs may be infrequent. HCs are invariably present in the bone marrow; but, per- haps because of the extensive fibrosis characteristic of...