The basic phenomena of intra- and intercellular communication and the transport signals within and between the cells controlling cardiac function are described and discussed in this volume. The amazing synchronization of millions of cells and billions of nanoscale molecular motors, ion gates, and ion pumps assure normal cardiac function; whereas disharmony and local transport and signal disruptions are the forecasters, and eventual causes, of pathologic conditions and heart failure.
Although this volume concentrates on basic phenomena, strong emphasis is given to the related...
The basic phenomena of intra- and intercellular communication and the transport signals within and between the cells controlling cardiac function are ...
Proceedings of the Eighth Henry Goldberg Workshop in title], held December 1992, in Bethesda, Maryland. Thirty-eight contributions address electromechanical activation, mechanics and microcirculation, microcirculation and metabolic transport, remodeling of muscle and vessels, and cardiac function a
Proceedings of the Eighth Henry Goldberg Workshop in title], held December 1992, in Bethesda, Maryland. Thirty-eight contributions address electromec...
A number of basic molecular and subcellular interactions affect the activation and performance of the heart in ways of interest to cardiologists. The 32 papers from a December 1994 workshop in Haifa, Israel, make the link between basic science and clinical practice in the molecular mechanisms of sar
A number of basic molecular and subcellular interactions affect the activation and performance of the heart in ways of interest to cardiologists. The ...
The focus of the conference was the pathway from basic genetics to cardiac function, highlighting the interface between structure and function at all levels of the cardiac system. The 30 papers strive to combine the analytical system approach and engineering principles with the multiple molecular an
The focus of the conference was the pathway from basic genetics to cardiac function, highlighting the interface between structure and function at all ...
The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologists, identify missing links, and catalyze new ideas. (2) To relate basic microscale phenomena to the global, clinically manifested cardiac function. (3) To relate conceptual modeling and quantitative analysis to experimental and clinical data. (4) To encourage international cooperation so as to disperse medical and technological knowhow and lead to better understanding of the cardiac system. The first Henry Goldberg Workshop, held in Haifa in...
The Henry Goldberg Workshops were set up to address the following goals: (1) To foster interdisciplinary interaction between scientists and cardiologi...
The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of interacting phenomena, from ionic microscopic transport, membrane channels and receptors through cellular metabolism, energy production to fiber mechanics, microcirculation, electrical activation to the global, clinically observed, function, which is measured by pressure, volume, coronary flow, heart rate, shape changes and responds to imposed loads and pharmaceutical challenges. It is a complex interdisciplinary system requiring the joint...
The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of ...
The tenth Henry Goldberg Workshop is an excellent occasion to recall our goals and celebrate some of our humble achievements. Vision and love of our fellow man are combined here to: 1) Foster interdisciplinary interaction between leading world scientists and clinical cardiologists so as to identify missing knowledge and catalyze new research ideas; 2) relate basic microscale, molecular and subcellular phenomena to the global clinically manifested cardiac performance; 3) apply conceptual modelling and quantitative analysis to better explore, describe, and understand cardiac physiology; 4)...
The tenth Henry Goldberg Workshop is an excellent occasion to recall our goals and celebrate some of our humble achievements. Vision and love of our f...
The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of interacting phenomena, from ionic transport, membrane channels and receptors through cellular metabolism, energy production to fiber mechanics, microcirculation, electrical activation to the global, clinically observed, function, which is measured by pressure, volume, coronary flow, heart rate, shape changes and responds to imposed loads and pharmaceutical challenges. It is a complex interdisciplinary system requiring the joint efforts of the...
The cardiac system represents one of the most exciting challenges to human ingenuity. Critical to our survival, it consists of a tantalizing array of ...
The basic mechanism underlying directional differences in excitability, con- duction velocity, andsafetyfactor thatleadtocircusmovementreentry incardiac muscle is generally attributed to a spatial difference in the refractory period as originally described by Mines [1] or to a depressed segment as described by Schmitt and Erlanger [2]. A departure from this depolarization in cardiac muscle involve quantities, such as Vmax' that are not directly descriptive of the underlying mechanisms of propagation.
The basic mechanism underlying directional differences in excitability, con- duction velocity, andsafetyfactor thatleadtocircusmovementreentry incardi...
