This book is the outgrowth of the COMETT II Course on Advanced Instru mentation, Data Interpretation, and Control of Biotechnological Processes organized by the Katholieke Universiteit Leuven and the Universiteit Gent, and held at Gent, Belgium, October 1994. The editors of the present volume were very fortunate to find all invited speakers prepared to write state-of-the-art expositions based on their lec tures. Special thanks are due to all of them. The result is an account of recent advances in instrumentation, data interpretation, and model based op timization and control of bioprocesses....