On March 8/9, 1976 a workshop on Mathematical Models in Medicine was held at Mainz (German Federal Republic) by the group of Mathe- matical Models of the Deutsche Gesellschaft fUr Medizinische Doku- mentation, Informatik und Statistik. Purpose of this conference was to bring together experts from the GFR and neighbouring countries working in this field to evaluate possibilities and limits of this area of research in discussions with interested participants. This issue of Lecture Notes contains the invited contributions as well as the relevan remarks made by the discussants. Corresponding to...