In response to the growing use of mass spectrometry in the clinical and biomedical fields, this book collects recent research involving electrospray ionization, neuronal systems, and structural modifications of proteins. The significant advances in instrumentation, methodology, experimentation presented herein will serve to expand the current concept of clinical mass spectrometry.

Tools, techniques, and progress in cancer biomarkers discovery

The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers. This book provides a comprehensive overview of current methodologies and technologies. It discusses biomarker discovery as a whole, rather than focusing on one specific marker or cancer. With information on both existing and potential biomarkers, Cancer Biomarkers:...

- __ ___ __ - __ e _e __ M-A-S-S S-P- -C-T-R-O-M- -T-R-Y in Morse code This volume collects descriptions of selected recent developments in state-of the-art mass spectrometric methods and reflects the broad-based approaches that mass spectroscopists apply to a variety of important clinical and bio medical problems. One chapter reviews current mass-spectrometric instrumen tation and techniques, and other chapters describe the use of mass-spectro metric methods for the analysis of diacylglycerylphospholipids; modifications to DNA molecules; the characterization of variant hemoglobins; and...

The definitive guide to mass spectrometry techniques in biology and biophysics

The use of mass spectrometry (MS) to study the architecture and dynamics of proteins is increasingly common within the biophysical community, and Mass Spectrometry in Structural Biology and Biophysics: Architecture, Dynamics, and Interaction of Biomolecules, Second Edition provides readers with detailed, systematic coverage of the current state of the art.

Offering an unrivalled overview of modern MS-based armamentarium that can be used to solve the most challenging problems in biophysics,...

- __ - ___ __ - - __ e _e __ M-A-S-S S-P--C-T-R-O-M--T-R-Y in Morse code This volume collects descriptions of selected recent developments in state-of- the-art mass spectrometric methods and reflects the broad-based approaches that mass spectroscopists apply to a variety of important clinical and bio- medical problems. One chapter reviews current mass-spectrometric instrumen- tation and techniques, and other chapters describe the use of mass-spectro- metric methods for the analysis of diacylglycerylphospholipids; modifications to DNA molecules; the characterization of variant hemoglobins; and...