Prior to 1974, the adrenergic receptors were known only in directly as entities that responded to drugs in a selective manner to mediate a variety of physiologically important responses. During the intervening years, our view of adrenergic receptors has changed dramatically. The availability of high affinity 125I-labeled radioligands selective for these receptors presaged an explosion of experimenta tion utilizing direct binding assays to establish the biochemical properties of the receptor protein. In the opening chapter, Stadel and Lefkowitz describe this development and its impact on our...
Prior to 1974, the adrenergic receptors were known only in directly as entities that responded to drugs in a selective manner to mediate a variety of ...
Prior to 1974, the adrenergic receptors were known only in directly as entities that responded to drugs in a selective manner to mediate a variety of physiologically important responses. During the intervening years, our view of adrenergic receptors has changed dramatically. The availability of high affinity 125I-labeled radioligands selective for these receptors presaged an explosion of experimenta tion utilizing direct binding assays to establish the biochemical properties of the receptor protein. In the opening chapter, Stadel and Lefkowitz describe this development and its impact on our...
Prior to 1974, the adrenergic receptors were known only in directly as entities that responded to drugs in a selective manner to mediate a variety of ...