Here is a dialog among worldwide experts across disciplines concerning theoretical frameworks and practical experiences to guide research and policy "towards environmental innovation systems." The contributors explore new directions of research at the border of two research traditions: systems of innovation and environmental innovations. The text examines the four main components of environmental innovation systems: conceptual foundations, empirical experiences, strategic approaches, and experiences with policy instruments.

There is clear evidence that in severe hypertension lowering blood pressure, by drug therapy decreases the incidence of major cardiovascular events. Recent studies suggest that such benefit may also extend to patients with mild to moderate hypertension. The putative benefits of drugs may be offset, however, by their adverse effects and a prime example is the increased incidence of impotence and metabolic disorders in patients on thiazide diuretics. There is, therefore, a real need to look further into the therapy of patients with mild to moderate hypertension. The ideal drug in such patients...

This book brings together papers presented at an international symposium on centrally acting antihypertensive agents held in Geneva, Switzerland, in association with the 10th Scientific Meeting of the International Society of Hypertension. A major focus of this symposium was the sympatholytic agent, clonidine, and was partly stimulated by the re cent development of an innovative transdermal system for administering this antihyper tensive drug. Although clonidine has been available to clinicians for several years, there has been a re cent reawakening of interest in this type of medication. The...