Combined positron emission tomography (PET) or single photon emission computed tomography (SPECT) with computed tomography (CT) has developed into the faste- growing imaging modality largely because combined PET or SPECT with CT data acquisition is highly synergistic in diagnosis and therapeutic evaluation. All currently available data indicate that integrated PET or SPECT/CT is more sensitive and s- ci?c than either of its constituent imaging methods alone and probably more so than images obtained from separate systems viewed side by side. The PET or SPECT/CT provides precise localization of...

Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast...

Combined positron emission tomography (PET) or single photon emission computed tomography (SPECT) with computed tomography (CT) has developed into the faste- growing imaging modality largely because combined PET or SPECT with CT data acquisition is highly synergistic in diagnosis and therapeutic evaluation. All currently available data indicate that integrated PET or SPECT/CT is more sensitive and s- ci?c than either of its constituent imaging methods alone and probably more so than images obtained from separate systems viewed side by side. The PET or SPECT/CT provides precise localization of...

This handbook will provide updated information on nuclear medicine and molecular imaging techniques as well as its clinical applications, including radionuclide therapy, to trainees and practitioners of nuclear medicine, radiology and general medicine. Updated information on nuclear medicine and molecular imaging are vitally important and useful to both trainees and existing practitioners. Imaging techniques and agents are advancing and changing so rapidly that concise and pertinent information are absolutely necessary and helpful. It is hoped that this handbook will help readers be better...

Advanced routine imaging techniques have made it possible to diagnose localized abnormalities often before they have produced irreversible damage. PET permits visualization of the metabolic or physiologic characteristics of tumors. MRI shows exclusive morphologic abnormalities, and functional MRI depicts the motor and sensory status in the vicinity of tumors. MRS offers biochemical information of tumors and surrounding normal tissues. Combining PET, MRI and MRS information we should be able to differentiate tumors from non-tumor lesions, to characterize types or grades of tumors, and to...

This volume is unique in reporting on strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. It also includes updated information on the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.