Novel molecular motifs named immunoreceptor tyrosine-based inhibition motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of an increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research, and with potential clinical applications. The present volume contains 15 reviews written by authors who made significant contributions to the identification of ITIM-bearing molecules and the study of...

3D design is now a key technology for effective collaboration between manufacturing companies. Since the introduction of light-weight 3D data technology, "post-3D CAD/CAM/CAE data" is now compatible for use across manufacturing, sales and marketing processes. The successful use of 3D data throughout such processes has become indispensable for the competitive strength of companies in the manufacturing industry.

For a company to survive and win in the manufacturing industry, it must not only accumulate light-weight 3D data, but also share this information within the company...

Marek's disease virus (MDV) is a herpesvirus which causes a lymphoproliferative disorder of the domestic chicken worldwide. This serious economical problem caused by MDV was mostly solved by development of an effective vaccine against MDV. The development of live vaccines against the disease is remarkable as it has led to the first example of a commercially available vaccine against cancer as well as against diseases caused by herpesviruses. This volume gives an overview on many aspects of MDV research and summarizes advances in the field. The topics include the history, biology, and...