Hemoglobin is an iron-containing protein in red blood cells that transports oxygen to tissues throughout the body. The abundance, stability, and oxygen-carrying properties of hemoglobin can be altered by genetic mutations. More than 1000 hemoglobin disorders are known; hemoglobinopathies (e.g., sickle cell disease) and thalassemias are some of the most common human genetic diseases worldwide. Written and edited by experts in the field, this collection from Cold Srping Harbor Perspectives in Biology covers all aspects of hemoglobin and its diseases. Contributors examine the structure,...