In 1890, just a few years after the discovery of the chromosomes, David Paul Hansemann, a pathologist-in-training with the famous Rudolph Virchow in Berlin, produced a theory of the pathogenesis of cancer involving the key current concept: that the first change which occurs in cancer is an alteration of the hereditary material of a normal cell at the site where the cancerous process begins.
In the process of linking cancer to chromosomal material, Hansemann coined the terms "anaplasia" and "dedifferentiation." These terms have remained the basis of descriptive...
In 1890, just a few years after the discovery of the chromosomes, David Paul Hansemann, a pathologist-in-training with the famous Rudolph Virchow i...
