Less than twenty years ago photolithography and medicine were total strangers to one another. They had not yet met, and not even looking each other up in the classi?eds. And then, nucleic acid chips, micro?uidics and microarrays entered the scene, and rapidly these strangers became indispensable partners in biomedicine. Asrecentlyastenyearsagothenotionofapplyingnanotechnologytothe?ghtagainstd- ease was dominantly the province of the ?ction writers. Thoughts of nanoparticle-vehicled deliveryoftherapeuticalstodiseasedsiteswereanexerciseinscienti?csolitude, andgrounds for questioning one's...
Less than twenty years ago photolithography and medicine were total strangers to one another. They had not yet met, and not even looking each other up...
In 1991, my newly formed researchgroupat Berkeley was working intensely in the area of continuum-level constitutive relationships that could be obtained in a deductive mannerfrom microstructuralinformationthroughthemethods of homogenization theory. Of particular interest was the application of such methods to structural problems in the blossoming field of micromechanical devices. In this context it was becoming evident that we needed to learn to navigate through the continuum/discrete interface. Such were the circumstances when Vladimir Granik came to visit us at Berkeley for the first time....
In 1991, my newly formed researchgroupat Berkeley was working intensely in the area of continuum-level constitutive relationships that could be obtain...