The beginning of life may be a miracle to some, and a mystery to others, but it is certainly one of the most exciting and perhaps controversial fields of scientific investigation in the 21st century. Among the metazoa, life begins when an egg is fertilized by a sperm. The sperm provides a genetic blueprint from the father and perhaps some critical proteins. The egg provides a genetic blueprint from the mother together with a large reservoir of mRNAs and proteins that are required for DNA replication, cell division and the onset of zygotic gene expression. All of the thousands of genes in...
The beginning of life may be a miracle to some, and a mystery to others, but it is certainly one of the most exciting and perhaps controversial fields...
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trillion meters of DNA And yet, with only two exceptions, the genome is replicated once and only once each time a cell divides. How is this feat accomplished? What happens when errors occur? This book addresses these questions by presenting a thorough analysis of the molecular events that govern DNA replication in eukaryotic cells. The association between genome replication and cell proliferation, disease pathogenesis, and the development of...
At least 5 trillion cell divisions are required for a fertilized egg to develop into an adult human, resulting in the production of more than 20 trill...
Marcel Mechali Melvin L. Depamphilis Stephen D. Bell
DNA replication is essential for the propagation of life on Earth. Cells in living organisms must be able to synthesize a complete copy of their DNA with extraordinary precision, so that they can pass this genetic material on to their descendants. DNA replication involves the coordinated interplay and regulation of many complex protein assemblies during the various stages of cell division. When these processes go awry, cancer and other diseases can ensue. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all aspects of DNA...
DNA replication is essential for the propagation of life on Earth. Cells in living organisms must be able to synthesize a complete copy of their DNA w...
Mammalian Preimplantation Development, the latest volume in the Current Topics in Developmental Biology series covers mammalian preimplantation development, and includes contributions from an international board of authors. The book's chapters provide a comprehensive set of reviews covering such topics as cell proliferation, cell differentiation, and biological significance.
Covers the area of mammalian preimplantation development
Includes contributions from an International board of authors
Provides a comprehensive set of reviews covering such...
Mammalian Preimplantation Development, the latest volume in the Current Topics in Developmental Biology series covers mammalian preimplantat...
