Locality is a fundamental restriction in nature. On the other hand, adaptive complex systems, life in particular, exhibit a sense of permanence and time- lessness amidst relentless constant changes in surrounding environments that make the global properties of the physical world the most important problems in understanding their nature and structure. Thus, much of the differential and integral Calculus deals with the problem of passing from local information (as expressed, for example, by a differential equation, or the contour of a region) to global features of a system's behavior (an...