Juneann W. Murphy Juneann W. Murphy Herman Friedman
Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, including fungi. Because of the devastating acquired immunodeficiency syndrome (AIDS) epidemic, caused by the human immunodeficiency retrovirus, it is now accepted that suppressed immune responses, especially cellular immu nity, are important contributors to increased individual susceptibility to opportunistic infections-including infections caused by fungi which were at one time thought to be very lowly or nonpathogenic. Within the last few years,...
Biomedical scientists widely acknowledge that individuals' immune respon siveness is important in resistance to infections by microorganisms, includin...
Peter G. Medveczky Mauro Bendinelli Herman Friedman
Although virology and immunology are now considered separate disciplines, history shows that these areas ofinvestigation always overlapped and one cannot really exist without the other. This trend has become particularly significant and fruitful in the past few years in the area of herpesvirus research. The genomes of the most important herpesviruses have been sequenced, a significant portion of their genes have been identified, and many secrets of regulation of gene expr- sion have been unraveled. Now this progress sets the stage for a true revolution in herpesvirus research: analysis of...
Although virology and immunology are now considered separate disciplines, history shows that these areas ofinvestigation always overlapped and one can...
Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but can be rapidly invasive, spreading through the tissues, invading bone, and seeding the bloodstream to produce a fulminant picture of septic shock, disseminated intravascular coagulation, and rapid death. Moreover, most strains of staph infections are becoming resistant to most antibiotics, thus posing a significant problem for hospitals and health care facilities. This book, a volume in the Infectious Agentsand Pathogenesis...
Staphylococcus aureus is now acknowledged as being the most important bacterial pathogen of humans. It usually produces localized disease but...
The discovery and concept that Helicobacter pylori is associated with gastric disease including gastric cancer which is one of the most common and frequently lethal forms of malignancy, heralded a new and rapidly expanding field recognizing the emergence of many new pathogens and disease syndromes in clinical medicine, as well as basic infectious disease research. There is now an extensive and widely known literature of how H. pylori is involved in a wide variety of disease syn dromes. As summarized in the introductory chapter of this volume, many major advances have been made in diagnosis,...
The discovery and concept that Helicobacter pylori is associated with gastric disease including gastric cancer which is one of the most common and fre...
The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences of this activity. For example, it is recognized that marijuana is currently widely used as a recreational drug in the United States as well as other countries. Similarly, abuse of cocaine, especially crack cocaine, is considered to be an epidemic. The war on drugs by the US Government was directly aimed at the illicit use of cocaine, marijuana, and opiates as well as other drugs of abuse. Furthermore, alcohol is also considered a major problem...
The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences ...
An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV.
Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey,...
An AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between...
The threat of bioterrorism has become a major challenge for the twenty-?rst century. However, the potentials of infectious agents as bioweapons have been recognized for centuries. Throughout history there have been attempts to i- tiate infectious disease outbreaks and epidemics during warfare. In the last decade the attention of the biomedical community, as well as governments and the United Nations, has increasingly focused on the threat of bioterr- ism, especially the use of biological and/or chemical weapons against military and civilian populations. As an example, there is now much...
The threat of bioterrorism has become a major challenge for the twenty-?rst century. However, the potentials of infectious agents as bioweapons have b...
Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been new developments in this field including the publication of three whole genome sequences, the discovery of a developmental cycle and novel cyst-like highly infectious form, and the bacteria have been used as a probe for macrophage cellular function to unravel fundamental new knowledge in the area of cellular biology. Legionella has also become a model system for the study of innate as well as adaptive immunity. Information on Legionella continues to...
Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. There have been new developm...
Herman Friedman Thomas W. Klein Andrea L. Friedman
Psychoneuroimmunology is the emerging science devoted to studying the two-way relationship between the nervous and immune systems. Psychoneuroimmunology, Stress, and Infection highlights the latest information concerning microbial infections in both man and animals as related to stress and especially stress hormones. The volume focuses on psychoneuroimmunology as it impacts the immune system in general and also the relationship between neurological events which influence susceptibility and/or resistance to infectious agents such as bacteria, fungi and viruses, as well as parasites....
Psychoneuroimmunology is the emerging science devoted to studying the two-way relationship between the nervous and immune systems. Psychoneuroimmunolo...
As a group, rickettsiae, and related bacteria, contain a number of human pathogens that have recently named as causes of emerging diseases'. This unique volume offers a thorough and current review of information on the pathogenesis and immune response elicited by memebers of the genera Rickettsia, Ehrlichia, Coxiella, Orlentia, and Bartonella, in contributions authored by the expert clinicians and researchers who work with these organisms.
As a group, rickettsiae, and related bacteria, contain a number of human pathogens that have recently named as causes of emerging diseases'. This uniq...
