Following A. N. Whitehead, this book takes up the principal challenge facing a natural philosopher who wishes to engage with Nature while rescuing both Life and Thought from materialistic approaches which rob them of their 'quicknesses'. Selecting certain insights and intuitions from the writings of Peirce, Coleridge, Deleuze and Nietzsche, the author proffers a remedy for the pervasive nihilism of 'the moderns' which illustrates Deleuze's suggestion that philosophy should be imaged as a dynamic collage that is forever in the making.