Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network. The mouse offers many advantages for the use of genetics to study human biology and disease, unmatched among other m- mals. Its development, body plan, physiology, behavior, and diseases have much in common, based on the fact that 99% of the human genes have a mouse ortholog. The investigation of gene function using mouse models is based on many years of tech- logical development. In the two decades...

Diplomarbeit aus dem Jahr 1996 im Fachbereich Gesundheitswissenschaften, Note: 2,0, Universitat Trier (Unbekannt), Sprache: Deutsch, Abstract: Inhaltsangabe: Einleitung: Seit ungefahr zwanzig Jahren explodieren die Gesundheitsausgaben - zumindest vermittelt der intensive Gebrauch der Metapher einer Kostenexplosion im Gesundheitswesen einen solchen Eindruck. Zwar scheint eine derartige Dramatik bei genauerer Betrachtung der Ausgabenentwicklung als Anteil am Bruttosozialprodukt sowohl in zeitlicher Entwicklung als auch im internationalen Vergleich ubertrieben, und die Finanzierungsprobleme der...

Following the completion of the mouse and human genome sequences, a major challengeisthefunctionalcharacterizationofeverymammaliangeneandthedeciph- ing of their molecular interaction network. The mouse offers many advantages for the use of genetics to study human biology and disease, unmatched among other m- mals. Its development, body plan, physiology, behavior, and diseases have much in common, based on the fact that 99% of the human genes have a mouse ortholog. The investigation of gene function using mouse models is based on many years of tech- logical development. In the two decades...