Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ESR is the only technique which has the potential for direct detection of radicals but in biological systems even these must be trapped by a spin-trapping agent. Thus most investigations involve recognition of indicators of the presence of radicals in vivo or "FOOTPRINTS" of radical-mediated damage.
Techniques in Free Radical Research assembles and critically assesses the most relevant and reliable experimental approaches used...
Free radical species are generally short-lived due to their high reactivity and thus direct measurement and identification are often impossible. ES...