The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control and could be forgotten. FMD proved to be an endemic disease in many countries and continues to pose a major threat to animal health worldwide. The development of more effective and socially acceptable diagnosis and control measures is essential to effectively combat this devastating virus. Foot and Mouth Disease: Current Perspectives benefits researchers by presenting the latest developments resulting from the upsurge in data concerning...
The shock following the recent outbreak of foot-and-mouth disease (FMD) in the UK dispelled the notion that this disease was permanently under control...
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it...
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccin...
Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mechanisms. The central topics of this volume are the origins of the quasispecies concept, and the implications of quasispecies dynamics for viral populations.
Continuous genetic variation and selection of virus subpopulations in the course of RNA virus replications are intimately related to viral disease mec...
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical...
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating ...
This book is required reading for everyone involved in FMD and is an important acquisition for all microbiology libraries. The volume provides essential scientific background on FMD and its etiological agent, FMD virus, as well as comprehensive, interdisciplinary and up-to-date information on basic research findings and applied developments contributing to FMD control. The eighteen chapters have been written by leading FMD researchers. Topics include genome...
This book is required reading for everyone involved in FMD and is an important acquisition for all microbiology l...
