This fifth volume of Research Methods in Neurochemistry represents a milestone in that it marks almost a decade since the inception of the series. Over these ten years there has been an almost exponential growth in neuro chemistry accompanied by numerous technical developments. This is the justification for our series; inevitably we have only been able to cover a frac tion of the methodological innovations of the last decade, but we have tried as much as possible to create a balance between the different approaches and philosophies in the study of the chemical basis of brain function. Thus...