The narrow gauge railroad arrived in the United States in the late nineteenth century. Based on the Welsh two-foot gauge, the American narrow gauge was expanded by railroad engineers to a three-foot gauge that became the standard track width for narrow gauge railroads in the United States. Maine, however, adopted the two-foot gauge that was developed by George E. Mansfield in Massachusetts. The narrow track width was ideally suited to the mountainous terrain, and the maneuverability of the trains proved highly beneficial to companies and passengers traveling to remote locations. The narrow...

Principles of Drug Therapy, Second Edition provides comprehensive coverage of current drug therapy in neurology while providing the background information that neurologists and other clinicians need to understand its rationale. The range of new drugs available for treatment of neurological disorders is expanding rapidly along with rapid advances in the neurosciences that are uncovering disease mechanisms. Although there are many sources of drug information, most are limited to basic information about indications, dose and side effects. However the complexity of the nervous system is...