This new edition reflects advances in the diagnosis and classification of bone tumours made over the 20 years since the first edition appeared. Although still based on routine light microscopy, the revised classificationbenefits from immunohistochemical and molecular biological findings. It discusses new entities, such as intraosseous well differentiated osteosarcoma, round-cell osteosarcoma, and clear-cell chondrosarcoma. It deals with the difficulties of diagnosis within the group of malignant roundcell tumours, such as the distinction between Ewing sarcoma and primitive neuroectodermal...

More than ten years have elapsed since the publication of the first edition of Tumors and Tumorlike Lesions of Bone and Joints in 1981. During this period significant progress has been made in diagnosis, and particularly in staging and treatment of bone tumors. In most centers, limb-sparing surgery has replaced the more radical ablative surgery, with or without preoperative chemotherapy. This became possible due to the introduction and increased application of newer high-quality imaging techniques (CT and MRI) and in particular the use of new cytomorphologic methods of diagnosis, especially...