Presents a collection of HLA phenotyping and genotyping techniques. This work covers topics including microlymphocytotoxicity assay, monoclonal antibodies, complement testing, serum screening for HLA antibodies, lymphocytotoxic crossmatching, and mixed and primed lymphocyte testing.

With advances in our understanding of the molecular biology of human diseases and the development of efficient gene transfer techniques, the treatment of such diseases as cancer and infectious disease using gene therapy, has progressed from a distant prospect to a distinct possibility in a very short period of time. The development of gene transfer methods which are suitable for different forms of therapy has been a major topic of research over the past several years. A common goal of this research has been to achieve the efficient delivery of genes into cells. The successful implementation...

This volume covers developments in cancer treatment using various gene delivery systems. These include cytokine gene tranfer, delivery of anti-ras DNA by retrovial vector, and the injection of allogeneic HLA DNA via liposomes.