Genetic Data Analysis, first published in 1990, became the standard reference for ways to interpret discrete population genetic data. Genetic Data Analysis II retains the strengths of the original book and, based upon the suggestions of users, includes many new features, notably the revision of Chapter 10 (Phylogeny Reconstruction) to incorporate newer methods, and new chapters on Linkage and Individual Identification.

This volume contains a selection of chapters base on papers presented at the Fourth Seattle Symposium in Biostatistics: Clinical Trials. The symposium was held in 2010 to celebrate the 40th anniversary of the University of Washington School of Public Health and Community Medicine. It featured keynote lectures by David DeMets and Susan Ellenberg and 16 invited presentations by other prominent researchers. The papers contained in this volume encompass recent methodological advances in several important clinical trials research, such as biomarkers, meta-analyses, sequential and adaptive clinical...