Greaves explains why the old paradigms of infectious diseases or genetic disorders have proved fruitless in analysing causes of cancer, and claims that by looking at cancer in its evolutionary context, we can begin to answer some of the big questions. Every day, 1500 Americans die of cancer, and yet for most of us this deadly disease remains mysterious. Why is it so common? Why are there so many different causes? Why does treatment so often fail? What, ultimately, is cancer? In this fascinating new book, a leading cancer researcher offers general readers clear and convincing answers to these...
Greaves explains why the old paradigms of infectious diseases or genetic disorders have proved fruitless in analysing causes of cancer, and claims tha...
This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer...
This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progress...