A textbook for a course in the biology of aging, developed from a European Commission research program identifying the links between aging and the onset of age-related diseases. Identifies the status and trends of research into such topics as the stability of the nuclear and mitochondrial genomes, t

Esteemed researchers from different European laboratories provide state-of-the-art studies on biology and ageing, along with guidelines for future investigations. They cover such issues in molecular gerontological research as regulation of gene expression from DNA to RNA to functional proteins, origin of various age-associated diseases, genetic regulation of ageing and longevity, and different mechanisms of defense and repair. Other contributions evaluate new technologies, including transgenic organisms, and the use of nutritional and chemical modulators of ageing and lifespan.