A chain condition is a property, typically involving considerations of cardinality, of the family of open subsets of a topological space. (Sample questions: (a) How large a fmily of pairwise disjoint open sets does the space admit? (b) From an uncountable family of open sets, can one always extract an uncountable subfamily with the finite intersection property. This monograph, which is partly fresh research and partly expository (in the sense that the authors co-ordinate and unify disparate results obtained in several different countries over a period of several decades) is devoted to the...