Bryan Williams and his international team of collaborators provide the reader with their views for treatment of diabetes associated with hypertension and the prevention of subsequent coronary artery disease and other disorders. Diabetes mellitus, particularly non-insulin-dependent diabetes Type 2, is a common disease and, even though insulin has been around for seventy years, this endocrine disorder still reduces the life expectancy of diabetic patients because of the development of long-term complications, including hypertension. Hypertension occurs twice as often in diabetic patients as in...

WT1 is a DNA Binding Protein Containing Four C2H2 Zinc Fingers ...89 The DNA Binding Domain ofWT1 ********************************************** *** 90 WT1 Inhibits Tag and SV40 Origin Dependent Replication ...97 WT1 is an Unusual C2H2 Zinc Finger Protein ...98 WT1 is a Transcriptional Regulator ...99 Possible Downstream Targets ofWT1 Transcriptional Regulation ...103 Protein-Protein Interactions Involving WT1 ...104 Other Factors that May Contribute to or Modify the Cellular Function ofWT1 ...104 WT1 and Apoptosis ...106 Conclusion ...107 7. Naturally Occurring Mutations in the WTJ Gene...