With almost half the world's population, Asia will determine the future of the global HIV/AIDS pandemic. There is a significant risk of a large-scale HIV/AIDS epidemic in the region. And many countries have already begun the fight: lessons have been learned in various contexts, including experiences from Thailand, the Philippines, Indonesia, and Papua New Guinea. Governments, civil society, and other partners are key players in this response. However, with new methods of funding, issues of capacity, and an evolving epidemic, responses must take into account five key challenges: political...