Extensive discoveries have been made about the roles of the neurotransmitter substances noradrenaline and dopamine in human beings as well as in experimental animals. The book starts with a description of the anatomy of the catecholamine pathways of the brain and a summary of the pharmacological manipulations available for studying them. Stephen Mason's main concerns, however, are with the studies of the part played by these brain systems in motor behaviour, learning and reward mechanisms, and cognitive and vegetative behaviour. Finally, he deals with the catecholamines in human clinical...