Sherlock Holmes's sister, Enola, is back on another case

Enola Holmes is being hunted by the world's most famous detective?her own brother, Sherlock Holmes. But while she is on the run in the world's biggest, darkest, dirtiest city, she discovers a hidden cache of charcoal drawings and feels as if she is a soul mate to the girl who drew them. But that girl, Lady Cecily, has disappeared without a trace. Braving the midnight streets, Enola must unravel the clues to find this left-handed lady, but in order to save her, Enola risks revealing more than she should. Will she be able to keep her...

After Enola Holmes encounters her friend Lady Cecily hiding behind a pink fan, she realizes Cecily is in danger. Enola soon discovers Cecily is being held hostage in an orphanage and faces a forced marriage.