Since the publication of the previous volumes many new aspects of the physical and life sciences have been developed in which the properties of water play a dominant role. The present volume and its companion, still in preparation, deal with topics that were already mentioned in the preface to Volume 5 as gaining in importance.

to arrive at some temporary consensus model or models; and to present reliable physical data pertaining to water under a range of conditions, i.e., "Dorsey revisited," albeit on a less ambitious scale. I should like to acknowledge a debt of gratitude to several of my col leagues, to Prof. D. J. G. Ives and Prof. Robert L. Kay for valuable guidance and active encouragement, to the contributors to this volume for their willing cooperation, and to my wife and daughters for the understanding shown to a husband and father who hid in his study for many an evening. My very special thanks go to Mrs....

vi the information collected and discussed in this volume may help toward the achievement of such an objective. I should like to express my debt of gratitude to the authors who have contributed to this volume. Editing a work of this nature can strain long- established personal relationships and I thank my various colleagues for bearing with me and responding (sooner or later) to one or several letters or telephone calls. My special thanks once again go to Mrs. Joyce Johnson, who bore the main brunt of this seemingly endless correspondence and without whose help the editorial and referencing...

Proteins are the servants of life. They occur in all com- nent parts of living organisms and are staggering in their fu- tional variety, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different p- teins, fulfilling a wide range of life-supporting roles. Additions to the total number of known proteins are being made on an increasing scale through the discovery of mutant strains or their production by genetic manipulation. The total international protein literature could fill a medi- sized building and is growing at an ever-increasing rate. The...

Proteins are the servants of life. They occur in all component parts of living organisms and are staggering in their functional var- ty, despite their chemical similarity. Even the simplest single-cell organism contains a thousand different proteins, fulfilling a wide range of life-supporting roles. Their production is controlled by the cell's genetic machinery, and a malfunction of even one protein in the cell will give rise to pathological symptoms. Additions to the total number of known proteins are constantly being made on an increasing scale through the discovery of mutant strains or...

This Volume, the last of the series, is devoted to water in its metastable forms, especially at sub-zero temperatures. The past few years have wit- nessed an increasing interest in supercooled water and amorphous ice. If the properties of liquid water in the normal temperature range are already eccentric, then they become exceedingly so below the normal freezing point, in the metastable temperature range. Water can be supercooled to -39C without too much effort, and most of its physical properties show a re- markable temperature dependence under these conditions. Although ade- quate...

This volume is the last in the series comprising "Water-A Comprehensive Treatise. " It was originally planned to combine aqueous solutions of macro- molecules and disperse systems in one volume, but largely because of the extensive coverage required by recent developments in aqueous solutions of proteins and synthetic polymers I decided to separate topics dealing with water in disperse systems. The systems treated in the present volume are of a complex nature so that the theoretical frameworks established earlier in Volume 1 and utilized in Volumes 2 and 3 cannot at the present time be...